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2015

Joseph R Kasper and Chiwook Park. Ligand binding to a high
energy partially unfolded protein. Protein Science 24, 129-137 (2015)
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2014

Chiwook Park. Probing transient partial unfolding in proteins by native-state proteolysis. Bio Design 2, 117-128 (2014).
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Jonathan P Schlebach, Nicholas B Woodall, James U Bowie, Chiwook Park. Bacteriorhodopsin folds through a poorly organized transition state. Journal of the American Chemical Society 136, 16574-16581 (2014).
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Joseph R Kasper, Elizabeth C Andrews, and Chiwook Park. Product inhibition in native-state proteolysis. PLoS One 9, e111416 (2014).
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Joseph R Kasper, Pei-Fen Liu, and Chiwook Park. Structure of a partially unfolded form of Escherichia coli dihydrofolate reductase provides insight into its folding pathway. Protein Science 23, 1728-1737 (2014).
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2012

Youngil Chang, Jonathan P Schlebach, Ross A VerHeul, and Chiwook Park. Simplified Proteomics Approach to Discover Protein-Ligand Interactions. Protein Science 21, 1280-1287 (2012).
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Pei-Fen Liu and Chiwook Park. Selective Stabilization of a Partially Unfolded Protein by a Metabolite. Journal of Molecular Biology 422, 403-413 (2012).
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Zheng Cao, Jonathan P Schlebach, Chiwook Park, and James U Bowie. Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state. Biochimica et Biophysica Acta - Biomembranes 1818, 1049-1054 (2012).
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Jonathan Schlebach, Zheng Cao, James U Bowie, and Chiwook Park. Revisiting Folding Kinetics of Bacteriorhodopsin. Protein Science 21, 97-106 (2012).
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2011

Pei-Fen Liu, Daisuke Kihara, and Chiwook Park. Energetics-based Discovery of Protein-Ligand Interactions on a Proteomic Scale. Journal of Molecular Biology 408, 147-162 (2011).

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Jonathan P Schlebach, Moon-Soo Kim, Nathan H Joh, James U Bowie, and Chiwook Park. Probing Membrane Protein Unfolding with Pulse Proteolysis. Journal of Molecular Biology 406, 545-551 (2011). (Cover article)
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2009

Youngil Chang and Chiwook Park. Mapping Transient Partial Unfolding by Protein Engineering and Native State Proteolysis. Journal of Molecular Biology 393, 543-556 (2009)
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Kiwon Youn and Chiwook Park. Investigating the Effect of Temperature on Transient Partial Unfolding by Proteolysis. Protein and Peptide Letters 16, 1093-1097 (2009)
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Pei-Fen Liu, Larisa Abramova, and Chiwook Park. Revisiting Absorbance at 230 nm as a Protein Unfolding Probe. Analytical Biochemistry 389, 165-170 (2009).
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Moon-Soo Kim, Jiao Song, and Chiwook Park. Determining Protein Stability in Cell Lysates by Pulse Proteolysis and Western Blotting. Protein Science 18, 1051-1059 (2009)
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Yu-Ran Na and Chiwook Park. Investigating Protein Unfolding Kinetics by Pulse Proteolysis. Protein Science 18, 268-276 (2009).
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2007

Chiwook Park, Sharleen Zhou, Jaqueline Gilmore, and Susan Marqusee. Energetics-Based Protein Profilining on a Proteomic Scale: Identification of Proteins Resistant to Proteolysis. Jounal of Molecular Biology 368, 1426-1437 (2007).
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2006

Chiwook Park and Susan Marqusee. Quantitative Determination of Protein Stability and Ligand Binding by Pulse Proteolysis. Current Protocols in Protein Science 20.11.1.-20.11.14. (2006).
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2005


Chiwook Park and Susan Marqusee. Pulse Proteolysis: A Simple Method for Quantitative Determination of Protein Stability and Ligand Binding. Nature Methods 2, 207-212 (2005).
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2004

Chiwook Park and Susan Marqusee. Probing the High Energy States in Proteins by Proteolysis. Jouranl of Molecular Biology 343, 1467-1476 (2004).
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Chiwook Park and Susan Marqusee. Analysis of the Stability of Multimeric Proteins by Effective ΔG and Effective m-values. Protein Science 13, 2553-2558 (2004).
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2003

Chiwook Park and Ronald T. Raines. Catalysis of Ribonuclease A is Limited by the Rate of Substrate Association. Biochemistry 42, 3509-3518 (2003).
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2002


Richele L. Abel, Marcia C. Haigis, Chiwook Park, and Ronald T. Raines. Fluorescence Assay for the Binding of Ribonuclease A to the Ribonuclease Inhibitor Protein. Analytical Biochemistry 306, 100-107 (2002).
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Peter A. Leland, Kristine E. Staniszewski, Chiwook Park, Bradley R. Kelemen, and Ronald T. RainesThe Ribonucleolytic Activity of Angiogenin. Peter A. Leland, Kristine E. Staniszewski, Chiwook Park, Bradley R. Kelemen, and Ronald T. Raines. Biochemistry 41, 1343-1350 (2002).
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2001

Chiwook Park and Ronald T. Raines. Quantitative Analysis of the Effect of Salt Concentration on Enzymatic Catalysis. Journal of the American Chemical Society 123, 11472-11479 (2001).
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Chiwook Park and Ronald T. Raines. Adjacent Cysteine Residues as a Redox Switch. Protein Engineering 14, 939-942 (2001).

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Chiwook Park, Bradley R. Kelemen, Tony A. Klink, Rozamond Y. Sweeney, Mark A. Behlke, Shad R. Eubanks, and Ronald T. Raines. Fast, Facile, and Hypersensitive Assays for Ribonucleolytic Activity. Methods in Enzymology 341, 81-94 (2001).

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Anwar M. Jardine, Demetres D. Leonidas, Jeremy L. Jenkins, Chiwook Park, Ronald T. Raines, K. Ravi Acharya, and Robert Shapiro. Cleavage of 3,5-Pyrophosphate-Linked Dinucleotides by Ribonuclease A and Angiogenin. Biochemistry 40, 10262-10271 (2001).

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Chiwook Park, L. Wayne Shultz, and Ronald T. Raines. Contribution of the Active-Site Histidine Residues of Ribonuclease A to Nucleic Acid Binding. Biochemsity 40, 4949-4956 (2001).

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2000

Chiwook Park and Ronald T. Raines. Dimer Formation by a Monomeric Protein. Protein Science 9, 2026-2033 (2000). (Cover article)
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Chiwook Park and Ronald T. Raines. Origin of the Inactivation of Ribonuclease A at Low Salt Concentration. FEBS Letters 468, 199-202 (2000).
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1998

David J. Quirk, Chiwook Park, James E. Thompson, and Ronald T. Raines. His...Asp Catalytic Dyad of Ribonuclease A: Conformational Stability of the Wild-Type, D121N, D121A, and H119A Enzymes. Biochemistry 37, 17958-17964 (1998).
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Medicinal Chemistry & Molecular Pharmacology | School of Pharmacy | Purdue University