G. Marc Loudon

Distinguished Professor of Medicinal Chemistry Emeritus, Purdue University

My research interests are in the area of bioorganic chemistry, with specific interests in the HIV protease, carboxy-terminal peptide degradation, enzyme mechanisms, and peptide synthesis. I do not lead a research group, but I serve on graduate-student committees. I have also been involved in several projects relating to the discovery and assessment of more effective ways of teaching organic chemistry.

Representative Publications:

  • Laurie L. Parker and G. Marc Loudon, "Case Study Using Online Homework In Undergraduate Organic Chemistry: Results and Student Attitudes," Journal of Chemical Education, 2013, 80(1), 37-44.
  • G. Marc Loudon and Mark E. Sharp, "Online Class Review," Journal of College Science Teaching, 2006, 35, 39-43.
  • V. L. Boyd, M. Bozzini, P. J. Guga, R. J. DeFranco, P.-M. Yuan, G. M. Loudon, and D. Nguyen, "Activation of the Carboxy Terminus of a Peptide for Carboxy-Terminal Sequencing," J. Org. Chem., 1995, 60, 2581-2587.
  • R. L. Geahlen, G. M. Loudon, L. A. Paige, and D. Lloyd, "A General Method for Preparation of Peptides Biotinylated at the Carboxy Terminus," Analytical Biochem. 1992, 202, 68-70.
  • G. M. Loudon, "Mechanistic Interpretation of pH-Rate Profiles," J. Chem. Educ. 1991, 68, 973-974.
  • G. M. Loudon, H.-S. Choi, and P. C. Andrews, "Chemical Recognition of Terminally Amidated Peptides," in Proc. Eleventh Amer. Peptide Symp., G.R. Marshall and J. Rivier, Editors, 1990, Escom, Leiden, pp. 433-434.
  • J. K. Blodgett and G. M. Loudon, "Cleavage vs. Transpeptidation in the Autodecomposition of Peptides Containing 2,4-Diaminobutanoic Acid and 2,3-Diaminopropanoic Acid Residues," J. Amer. Chem. Soc. 1989, 111, 6813-6821.
  • J. K. Blodgett, G. M. Loudon, and K. D. Collins, "Specific Cleavage of Peptides Containing an Aspartic(beta;-Hydroxamic Acid) Residue," J. Am. Chem. Soc. 1985, 107, 4305-4313.