The lab is using molecular, cellular, biochemical, genetic and imaging approaches to studying how cancer cell behaviors are regulated at the transcription and epigenetic levels. The ultimate goal is to develop novel anti-cancer agents for cancer treatment. We have developed several research programs that are integrated with technology development, basic biological research, and clinical translation. The current technology developments involve bimolecular fluorescence complementation (BiFC) and BiFC-derived technologies. The biological research is centered on the transcriptional and epigenetic regulation of cancer cell growth and therapeutic response. The clinical translational research is aimed at understanding the molecular mechanisms of therapy-resistant prostate cancer and development of novel therapeutics. In addition, we are developing novel treatment approaches for lung cancer and pancreatic cancer.
We have openings for graduate students and postdoctoral fellows.